Article
Lack of linkage between the endothelial nitric oxide synthase gene and hypertension.
Journal of human hypertension - 1 Jan 1996
Hunt S C, Williams C S, Sharma A M, Inoue I, Williams R R, Lalouel J M
Abstract excerpt
Nitric oxide is an important vasodilator formed in many tissues, including the vascular endothelium. Because of the relationship between nitric oxide and basal vascular tone, genes regulating nitric oxide have been suggested as candidate genes involved with the development of hypertension. At least three isoforms of nitric oxide synthase have been identified. Two of the isoforms, endothelial and inducible nitric...
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