Article
The effect of Y-chromosome alpha-satellite array length on the rate of sex chromosome disomy in human sperm.
Human genetics - 1 Jun 1996
Abruzzo M A, Griffin D K, Millie E A, Sheean L A, Hassold T J
Abstract excerpt
Trisomy is the leading known cause of mental retardation and pregnancy loss in humans, yet virtually nothing is known of the underlying nondisjunctional mechanisms. Since studies of other organisms suggest an association between centromere size or sequence and meiotic nondisjunction, we recently initiated studies to examine the effect of centromere size variation on human nondisjunction. In the present report, we...
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