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Article

Characterization of two transposon mutants from Haemophilus influenzae type b with altered lipooligosaccharide biosynthesis.

Biochemistry - 7 May 1996

Phillips N J, McLaughlin R, Miller T J, Apicella M A, Gibson B W

Abstract excerpt

Two isogenic mutants of Haemophilus influenzae type b (Hib) strain A2 were prepared by random m-Tn3(Cm) insertions into the 7.4-kb lsg (lipooligosaccharide synthesis genes) region of Hib DNA, which consists of seven complete and one partial open reading frame (orfs). Compared to the parent A2 strain which produces a complex mixture of lipooligosaccharides (LOS), the mutant strains 281.25 and 276.4 produced only a...

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Identifiers

PMID: 8639556
DOI: 10.1021/bi960059b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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