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Article

Stability of microsatellites and minisatellites in Bloom syndrome, a human syndrome of genetic instability.

Mutation research - 2 Apr 1996

Foucault F, Buard J, Praz F, Jaulin C, Stoppa-Lyonnet D, Vergnaud G, Amor-Guéret M

Abstract excerpt

Bloom syndrome (BS) is a human cancer-prone genetic disorder essentially characterized by a generalized genetic instability including a high level of sister chromatid exchanges (SCEs). Although mutator and hyper-Rec phenotypes of BS cells present analogies with those of bacteria and yeast defective in DNA mismatch repair, we report that (CA)(n) microsatellite alterations are undetectable in BS cells. Thus, our...

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Identifiers

PMID: 8637501
DOI: 10.1016/0921-8777(95)00047-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Stability of microsatellites and minisatellites in Bloom syndrome, a human syndrome of genetic instability.PMID 8637501Read ↗

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Genomic instability and cancer: lessons from analysis of Bloom's syndrome.Semantic proximity Read ↗

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Mutation of the murine Bloom's syndrome gene produces global genome destabilization.Semantic proximity Read ↗

Characterization of a new BLM mutation associated with a topoisomerase II alpha defect in a patient with Bloom's syndrome.Semantic proximity Read ↗

Relatively common mutations of the Bloom syndrome gene in the Japanese population.Semantic proximity Read ↗

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