Article
Mutations in a C. elegans Gqalpha gene disrupt movement, egg laying, and viability.
Neuron - 1 May 1996
Brundage L, Avery L, Katz A, Kim U J, Mendel J E, Sternberg P W, Simon M I
Abstract excerpt
We find that C. elegans egl-30 encodes a heterotrimeric G protein a subunit more than 80% identical to mammalian Gqalpha family proteins, and which can function as a Gqalpha subunit in COS-7 cells. We have identified new egl-30 alleles in a selection for genes involved in the C. elegans acetylcho...
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