Article
Transcription factor PU.1 mediates induction of c-fms in vascular smooth muscle cells: a mechanism for phenotypic change to phagocytic cells.
Molecular and cellular biology - 1 May 1996
Inaba T, Gotoda T, Ishibashi S, Harada K, Ohsuga J I, Ohashi K, Yazaki Y, Yamada N
Abstract excerpt
The macrophage colony-stimulating factor receptor encoded by the c-fms gene is expressed in vascular intimal smooth muscle cells isolated from atherosclerotic lesions. A combination of platelet-derived growth factor-BB and epidermal growth factor induces stable expression of c-fms in normal vascu...
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