Article
Upstream stimulatory factor 1 regulates osteopontin expression in smooth muscle cells.
Experimental cell research - 1 Aug 1999
Malyankar U M, Hanson R, Schwartz S M, Ridall A L, Giachelli C M
Abstract excerpt
Vascular smooth muscle cells (SMCs) undergo a dramatic phenotypic transition in response to injury and ex vivo culture that includes enhanced proliferation, migration, matrix deposition, and alterations in gene expression. Osteopontin is a good marker for the injury-induced SMC phenotypic state in vivo and in vitro. To identify transcription factors that might control the regulation of osteopontin expression, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
