Article
Sequence variation of latent membrane protein-1 of Epstein-Barr virus strains associated with hairy leukoplakia.
The Journal of infectious diseases - 1 Mar 1996
Palefsky J M, Berline J, Penaranda M E, Lennette E T, Greenspan D, Greenspan J S
Abstract excerpt
The Epstein-Barr virus (EBV) latent membrane protein (LMP)-1 is expressed in hairy leukoplakia (HL), but data on LMP-1 sequence variation of HL isolates are limited. Variation in the LMP-1 repeat region and presence of a 30-nt deletion were studied using DNA scrapings from 28 HL lesions. cDNAs from 3 different HL isolates were sequenced, 2 from lymphocyte cell lines (LCLs) generated using HL biopsy material. The...
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