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Article

Synonymous codon selection controls in vivo turnover and amount of mRNA in Escherichia coli bla and ompA genes.

Journal of bacteriology - 1 May 1996

Deana A, Ehrlich R, Reiss C

Abstract excerpt

A number of silent codon changes were made in two Escherichia coli genes. For the ompA gene, the replacement of seven consecutive frequently used codons with synonymous infrequently used codons reduced the ompA mRNA level and its half-life. For the bla gene, the exchange of 24 codons for the most frequently used synonymous codons extended the bla mRNA half-life. A modification of ribosome traffic could account...

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Identifiers

PMID: 8626345
DOI: 10.1128/jb.178.9.2718-2720.1996
PMCID: PMC178002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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