Article
Bacteriophage Mu repressor as a target for the Escherichia coli ATP-dependent Clp Protease.
The EMBO journal - 15 Jan 1996
Laachouch J E, Desmet L, Geuskens V, Grimaud R, Toussaint A
Abstract excerpt
Bacteriophage Mu repressor, which is stable in its wildtype form, can mutate to become sensitive to its Escherichia coli host ATP-dependent ClpXP protease. We further investigated the determinants of the mutant repressor's sensitivity to Clp. We show the crucial importance of a C-terminal, seven amino acid long sequence in which a single change is sufficient to decrease the rate of degradation of the protein. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.