Article
18. Genetics of breast cancer.
International journal of clinical practice - 1 Nov 2002
Irving M, Elmslie F, Berg J
Abstract excerpt
It is well known that breast cancer often occurs in clusters within families. This clustering can be attributed to mutations in the breast cancer susceptibility genes, BRCA1 and BRCA2, in 16% of familial cases. Women with a family history of breast cancer, in whom no mutation is identified, are still at increased risk of developing the disease. This review addresses methods for estimating and stratifying risk of...
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