Article
Bcl-2,Bax andp53 expression in B-CLL in relation toin vitro survival and clinical progression
22 Apr 1996
Abstract excerpt
Our previous data have shown that isolated leukemic cells from progressive chronic lymphocytic leukemia (B-CLL) patients respond to growth stimulation in vitro and express high levels of p53, immunoreactive with the configuration-specific antibody PAb 240. We have now analyzed the in vitro survival of B-CLL cells in relation to Bcl-2, Bax alpha and p53 expression and compared this with the clinical progression of...
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