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Article

bcl-2/bax mRNA expression ratio as prognostic factor in low-grade urinary bladder cancer

22 Apr 1996

Abstract excerpt

Apoptotic cell death represents an important mechanism for the precise regulation of cell numbers, and a defence mechanism against tumoral cell. bcl-2 and bax genes are known to be involved in the control of apoptotic pathways; in particular, the ratio between bcl-2 and bax represents a cell rheostat that is able to predict a cell's response toward life or death to an apoptotic stimulus. In the present study we...

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Share to Bladder and Urothelial Cancer Treatments
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Identifiers

PMID: 8608975
DOI: 10.1002/(sici)1097-0215(19960422)69:2<100::aid-ijc5>3.0.co;2-4

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