Article
An O-antigen processing function for Wzx (RfbX): a promising candidate for O-unit flippase.
Journal of bacteriology - 1 Apr 1996
Liu D, Cole R A, Reeves P R
Abstract excerpt
O antigen is the major cell surface antigen of gram-negative bacteria, and the genes responsible for its synthesis are located in a single gene cluster. The wzx (rbfX) gene, which is characteristic of the major class of O-antigen gene clusters, encodes a hydrophobic protein with 12 potential transmembrane segments. We demonstrate that a wzx mutant accumulates undecaprenol pyrophosphate-linked O units which appear...
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