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Article

Long-term toxicity studies of ozone in F344/N rats and B6C3F1 mice.

Toxicology letters - 1 Dec 1995

Boorman G A, Sills R C, Grumbein S, Hailey R, Miller R A, Herbert R A

Abstract excerpt

The toxicity and carcinogenicity of ozone was evaluated in Fischer 344/N rats and B6C3F1 mice exposed to 0, 0.12 (2 years only), 0.5 or 1.0 ppm ozone by inhalation for 2-year and lifetime exposures. A 2-year cocarcinogenicity study (male rats only) included the subcutaneous administration of 0, 0.1 or 1.0 mg/kg/body wt. of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) for the first 20 weeks along with...

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PMID: 8597069
DOI: 10.1016/0378-4274(95)03483-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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