Article
The similarity of phenotypic effects caused by Xp and Xq deletions in the human female: a hypothesis.
Human genetics - 1 Jul 1990
Therman E, Susman B
Abstract excerpt
We have collected from the literature adult nonmosaic women with the following aberrant X chromosomes: Xp- (52), Xq- (67), idic(Xp-)(10), idic(Xq-)(9), and interstitial deletions (12). Lack of Xp, and especially Xcen-Xp11 (b region), may cause full-blown Turner syndrome. However, individual Turner symptoms, including gonadal dysgenesis, otherwise seem to be randomly distributed with respect to the different Xp...
Topics
- Adolescent
- Adult
- Amenorrhea
- Chromosome Banding
- Chromosome Deletion
- Female
- Humans
- Menopause, Premature
- Models, Biological
- Mosaicism
- Phenotype
- Turner Syndrome