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Article

Molecular population genetics of ref(2)P, a locus which confers viral resistance in Drosophila.

Molecular biology and evolution - 1 Jan 1996

Wayne M L, Contamine D, Kreitman M

Abstract excerpt

The ref(2)P locus (2-54.2) is polymorphic for two allelic forms in natural populations of Drosophila melanogaster, ref(2)Po and ref(2)Pp. The latter allele confers resistance to the rhabdovirus sigma infecting wild populations. Previous work, based on a small sample of prescreened restrictive (resistant) and permissive (susceptible) alleles, identified a large number of amino acid replacement changes (7) relative...

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PMID: 8583891
DOI: 10.1093/oxfordjournals.molbev.a025555

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