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Article

Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in Drosophila melanogaster.

PLoS genetics - 1 Jan 2012

Magwire Michael M, Fabian Daniel K, Schweyen Hannah, Cao Chuan, Longdon Ben, Bayer Florian, Jiggins Francis M

Abstract excerpt

Variation in susceptibility to infectious disease often has a substantial genetic component in animal and plant populations. We have used genome-wide association studies (GWAS) in Drosophila melanogaster to identify the genetic basis of variation in susceptibility to viral infection. We found that there is substantially more genetic variation in susceptibility to two viruses that naturally infect D. melanogaster...

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Identifiers

PMID: 23166512
DOI: 10.1371/journal.pgen.1003057
PMCID: PMC3499358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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