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Article

The age and evolution of an antiviral resistance mutation in Drosophila melanogaster.

Proceedings. Biological sciences - 22 Aug 2007

Bangham Jenny, Obbard Darren J, Kim Kang-Wook, Haddrill Penelope R, Jiggins Francis M

Abstract excerpt

What selective processes underlie the evolution of parasites and their hosts? Arms-race models propose that new host-resistance mutations or parasite counter-adaptations arise and sweep to fixation. Frequency-dependent models propose that selection favours pathogens adapted to the most common host genotypes, conferring an advantage to rare host genotypes. Distinguishing between these models is empirically...

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Identifiers

PMID: 17550883
DOI: 10.1098/rspb.2007.0611
PMCID: PMC1914336

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