Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Drosophila insulator protein facilitates dosage compensation of the X chromosome min-white gene located at autosomal insertion sites.

Development (Cambridge, England) - 1 Nov 1995

Roseman R R, Swan J M, Geyer P K

Abstract excerpt

The suppressor of Hairy-wing [su(Hw)] gene encodes a zinc finger protein that binds to a repeated motif in the gypsy retrotransposon. These DNA sequences, called the su(Hw)-binding region, have properties of an insulator region because they (1) disrupt enhancer/silencer function in a position-dependent manner and (2) protect the mini-white gene from both euchromatic and heterochromatic position effects. To gain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Binding Proteins
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila

Share to Drosophila Proteins

Share to Gene Expression

Share to Heterozygote

Share to Nuclear Proteins

Share to Phenotype

Source

Identifiers

PMID: 8582271
DOI: 10.1242/dev.121.11.3573

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Drosophila insulator protein facilitates dosage compensation of the X chromosome min-white gene located at autosomal insertion sites.PMID 8582271Read ↗

The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects.Semantic proximity Read ↗

Dosage compensation of the Drosophila white gene requires both the X chromosome environment and multiple intragenic elements.Semantic proximity Read ↗

A sex-influenced modifier in Drosophila that affects a broad spectrum of target loci including the histone repeats.Semantic proximity Read ↗

Weakener of white (Wow), a gene that modifies the expression of the white eye color locus and that suppresses position effect variegation in Drosophila melanogaster.Semantic proximity Read ↗

PWWP mutants of the transcriptional cofactor JASPer divert promoter and enhancer activities and suppress position effect variegation in Drosophila.Semantic proximity Read ↗

Position-effect variegation, heterochromatin formation, and gene silencing in Drosophila.Semantic proximity Read ↗

The Lighten up (Lip) gene of Drosophila melanogaster, a modifier of retroelement expression, position effect variegation and white locus insertion alleles.Semantic proximity Read ↗

Functional organization of the white gene enhancer in Drosophila melanogaster.Semantic proximity Read ↗

Comparative analysis of position-effect variegation mutations in Drosophila melanogaster delineates the targets of modifiers.Semantic proximity Read ↗

Chromosomal structure is altered by mutations that suppress or enhance position effect variegation.Semantic proximity Read ↗

A balance between euchromatic (JIL-1) and heterochromatic [SU(var)2-5 and SU(var)3-9] factors regulates position-effect variegation in Drosophila.Semantic proximity Read ↗

Position-effect variegation and z1 mediated white repression in the In(1)wis system in Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.