Article
A Drosophila insulator protein facilitates dosage compensation of the X chromosome min-white gene located at autosomal insertion sites.
Development (Cambridge, England) - 1 Nov 1995
Roseman R R, Swan J M, Geyer P K
Abstract excerpt
The suppressor of Hairy-wing [su(Hw)] gene encodes a zinc finger protein that binds to a repeated motif in the gypsy retrotransposon. These DNA sequences, called the su(Hw)-binding region, have properties of an insulator region because they (1) disrupt enhancer/silencer function in a position-dep...
Topics
- Animals
- DNA Transposable Elements
- DNA-Binding Proteins
- Dosage Compensation, Genetic
- Drosophila
- Drosophila Proteins
- Eye
- Female
- Gene Expression
- Heterozygote
- Leucine Zippers
- Nuclear Proteins
- Phenotype
- Repressor Proteins
- Transgenes