Article
Cassia senna inhibits mutagenic activities of benzo[a]-pyrene, aflatoxin B1, shamma and methyl methanesulfonate.
Pharmacology & toxicology - 1 Oct 1995
al-Dakan A A, al-Tuffail M, Hannan M A
Abstract excerpt
Ethanol extract of Senokot tablets (Cassia senna concentrate used as vegetable laxative), was found to be non-mutagenic while it inhibited the mutagenicity of benzo[a]pyrene, shamma, aflatoxin B1 and methyl methanesulfonate in the Ames histidine reversion assay using the Salmonella typhimurium te...
Topics
- Aflatoxin B1
- Benzo(a)pyrene
- Biotransformation
- Cathartics
- Dose-Response Relationship, Drug
- Histidine
- Methyl Methanesulfonate
- Mutagenicity Tests
- Mutation
- Salmonella typhimurium
- Senna Extract
