Article
[The mutagenic activity of coal tar].
Eksperimental'naia onkologiia - 1 Jan 1990
Lycheva T A, Khitrovo I A, Kosoĭ G Kh, Khesina A Ia, Belitskiĭ G A
Abstract excerpt
Genotoxicity of tar samples collected at the Kemerovo and Altai by-product coke plants has been studied, the contribution of benz(a)pyrene (BP) into the total mutagenic activity of extracts being estimated. Both direct and indirect mutagenicity of the samples is determined in the Ames test. A direct mutagenic effect of coal tar may be attributed neither to the BP action nor to other polycyclic aromatic...
Topics
- Animals
- Benzo(a)pyrene
- Coal Tar
- Dose-Response Relationship, Drug
- Microsomes, Liver
- Mutagenicity Tests
- Mutagens
- Mutation
- Polycyclic Compounds
- Rats
- Salmonella typhimurium
