Antimutagenic activity of some saponins isolated from Calendula officinalis L., C. arvensis L. and Hedera helix L.

doi:10.1093/mutage/5.4.327

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Article

Antimutagenic activity of some saponins isolated from Calendula officinalis L., C. arvensis L. and Hedera helix L.

Mutagenesis - 1 Jul 1990

Elias R, De Méo M, Vidal-Ollivier E, Laget M, Balansard G, Dumenil G

Abstract excerpt

Thirteen saponins were isolated and identified from Calendula officinalis, C. arvensis and Hedera helix. Mutagenic and antimutagenic activities of these products were investigated using a modified liquid incubation technique of the Salmonella/microsomal assay. The Salmonella tester strain TA98 +/...

Topics

Animals
Benzo(a)pyrene
Chlorophyllides
Dose-Response Relationship, Drug
Male
Molecular Structure
Mutagenicity Tests
Mutation
Rats
Rats, Inbred Strains
Salmonella typhimurium
Saponins
Smoking

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