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Antimutagenic activity of some saponins isolated from Calendula officinalis L., C. arvensis L. and Hedera helix L.

Mutagenesis - 1 Jul 1990

Elias R, De Méo M, Vidal-Ollivier E, Laget M, Balansard G, Dumenil G

Abstract excerpt

Thirteen saponins were isolated and identified from Calendula officinalis, C. arvensis and Hedera helix. Mutagenic and antimutagenic activities of these products were investigated using a modified liquid incubation technique of the Salmonella/microsomal assay. The Salmonella tester strain TA98 +/- S9 mix was used. Screening of the antimutagenic activity was performed with a known promutagen: benzo-[a]pyrene (BaP)...

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PMID: 2204784
DOI: 10.1093/mutage/5.4.327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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