Article
Elastin gene mutations in transgenic mice.
Ciba Foundation symposium - 1 Jan 1995
Sechler J L, Sandberg L B, Roos P J, Snyder I, Amenta P S, Riley D J, Boyd C D
Abstract excerpt
We have constructed several rat tropoelastin minigene recombinants encoding the complete sequence of rat tropoelastin, two isoforms of rat tropoelastin and a truncated tropoelastin lacking the domains encoded by exons 19-31 of the rat gene. Coding and non-coding domains in all these recombinants were placed under the transcriptional control of 3 kb of the promoter domain of the rat tropoelastin gene. These...
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