Article
Dmcdc2 kinase is required for both meiotic divisions during Drosophila spermatogenesis and is activated by the Twine/cdc25 phosphatase.
Mechanisms of development - 1 Oct 1995
Sigrist S, Ried G, Lehner C F
Abstract excerpt
We have analyzed the requirement for Drosophila cdc2 kinase during spermatogenesis after generating temperature-sensitive mutant lines (Dmcdc2ts) by re-constructing mutations known to result in temperature sensitivity in fission yeast cdc2+. While meiotic spindles and metaphase plates were never...
Topics
- Amino Acid Sequence
- Animals
- Cell Differentiation
- Cyclin-Dependent Kinase 2
- Drosophila
- Drosophila Proteins
- Enzyme Activation
- Insect Hormones
- Insect Proteins
- Male
- Meiosis
- Molecular Sequence Data
- Mutation
- Phenotype
- Phosphorylation
- Protein Serine-Threonine Kinases
- Protein Tyrosine Phosphatases
- Proteins