The Drosophila cdc25 homolog twine is required for meiosis.

doi:10.1242/dev.116.2.405

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Article

The Drosophila cdc25 homolog twine is required for meiosis.

Development (Cambridge, England) - 1 Oct 1992

Courtot C, Fankhauser C, Simanis V, Lehner C F

Abstract excerpt

We have identified a second cdc25 homolog in Drosophila. In contrast to string (the first homolog identified in Drosophila) this second homolog, twine, does not function in the mitotic cell cycle, but is specialized for meiosis. Expression of twine was observed exclusively in male and female gonads. twine transcripts are present in germ cells during meiosis, and appear only late during gametogenesis, well after...

Topics

Amino Acid Sequence
Animals
Base Sequence
Drosophila
Female
Gene Expression
Genes
Male
Meiosis
Microscopy, Fluorescence
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oogenesis

Ovary

Phenotype

Sequence Homology, Amino Acid

Spermatogenesis

Testis

Source

Open in PubMed

Identifiers

PMID: 1286615
DOI: 10.1242/dev.116.2.405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1286615-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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