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Article

Significance of cytogenetic clonal evolution in chronic myelogenous leukemia.

1 Jan 1996

Abstract excerpt

PURPOSE: To describe the incidence and significance of clonal evolution patterns. PATIENTS AND METHODS: We analyzed 264 patients with Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) who developed clonal evolution between 1967 and 1993. RESULTS: The median survival time following clonal evolution was 19 months. Factors associated with worse survival (P < .01) were as follows: chromosome 17...

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Identifiers

PMID: 8558198
DOI: 10.1200/jco.1996.14.1.196

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