Article
Definition of an HLA-DPw2-restricted epitope on NS3, recognized by a dengue virus serotype-cross-reactive human CD4+ CD8- cytotoxic T-cell clone.
Journal of virology - 1 Oct 1993
Kurane I, Dai L C, Livingston P G, Reed E, Ennis F A
Abstract excerpt
We previously reported that the clone JK34 was cross-reactive for dengue virus types 1, 2, 3, and 4 and recognized NS3 (I. Kurane, M. A. Brinton, A. L. Samson, and F. A. Ennis, J. Virol. 65:1823-1828, 1991). In the present experiments, we defined the epitope at the amino acid level, with 93 15-me...
Topics
- Amino Acid Sequence
- Cross Reactions
- Cytotoxicity, Immunologic
- Dengue Virus
- Epitopes
- Genotype
- HLA-DP Antigens
- Humans
- Molecular Sequence Data
- RNA Helicases
- Serine Endopeptidases
- Serotyping
- T-Lymphocyte Subsets
- T-Lymphocytes, Cytotoxic
- Viral Nonstructural Proteins
