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Article

Differential phosphorylation of human tau isoforms containing three repeats by several protein kinases.

Archives of biochemistry and biophysics - 1 Apr 1996

Singh T J, Grundke-Iqbal I, Iqbal K

Abstract excerpt

The paired helical filaments (PHF) found in the brain of patients with Alzheimer disease (AD) are composed primarily of the microtubule-associated protein tau. Six isoforms of tau have been recognized and all are present in a hyperphosphorylated state in PHF. It is not known whether all tau isoforms serve equally well as substrates for various kinases. In this study we have compared the phosphorylation of human...

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Identifiers

PMID: 8638936
DOI: 10.1006/abbi.1996.0140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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