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Differential phosphorylation of human tau isoforms containing three repeats by several protein kinases.

Archives of biochemistry and biophysics - 1 Apr 1996

Singh T J, Grundke-Iqbal I, Iqbal K

Abstract excerpt

The paired helical filaments (PHF) found in the brain of patients with Alzheimer disease (AD) are composed primarily of the microtubule-associated protein tau. Six isoforms of tau have been recognized and all are present in a hyperphosphorylated state in PHF. It is not known whether all tau isofo...

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Genetic Variation
Kinetics
Repetitive Sequences, Nucleic Acid
Phosphorylation
Epitopes
Substrate Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Kinases

Calcium-Calmodulin-Dependent Protein Kinases

Source

Identifiers

PMID: 8638936
DOI: 10.1006/abbi.1996.0140

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8638936-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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