An incremental algorithm for efficient multipoint linkage analysis.

doi:10.1159/000154301

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Article

An incremental algorithm for efficient multipoint linkage analysis.

Human heredity - 1 Jan 2000

Kramer R W, Weeks D E, Chiarulli D M

Abstract excerpt

While much effort has gone into developing efficient algorithms for calculating multipoint likelihoods, these calculations still form a significant bottleneck in the construction of genetic linkage maps. Our approach to this problem is based on incremental processing techniques, which attempt to...

Topics

Algorithms
Genetic Linkage
Genotype
Humans
Likelihood Functions
Lod Score
Models, Genetic

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