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Article

Alignment of 700 globin sequences: extent of amino acid substitution and its correlation with variation in volume.

Protein science : a publication of the Protein Society - 1 Oct 1995

Kapp O H, Moens L, Vanfleteren J, Trotman C N, Suzuki T, Vinogradov S N

Abstract excerpt

Seven-hundred globin sequences, including 146 nonvertebrate sequences, were aligned on the basis of conservation of secondary structure and the avoidance of gap penalties. Of the 182 positions needed to accommodate all the globin sequences, only 84 are common to all, including the absolutely conserved PheCD1 and HisF8. The mean number of amino acid substitutions per position ranges from 8 to 13 for all globins...

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Identifiers

PMID: 8535255
DOI: 10.1002/pro.5560041024
PMCID: PMC2142974

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