Article
Estimating the fraction of invariable codons with a capture-recapture method.
Journal of molecular evolution - 1 Sept 1992
Sidow A, Nguyen T, Speed T P
Abstract excerpt
A codon-based approach to estimating the number of variable sites in a protein is presented. When first and second positions of codons are assumed to be replacement positions, a capture-recapture model can be used to estimate the number of variable codons from every pair of homologous and aligned...
Topics
- Biological Evolution
- Codon
- Computer Simulation
- Genetic Techniques
- Genetic Variation
- Likelihood Functions
- Molecular Sequence Data
