Article
Fibroblast growth factor receptors (FGFRs) localize in different cellular compartments. A splice variant of FGFR-3 localizes to the nucleus.
The Journal of biological chemistry - 22 Dec 1995
Johnston C L, Cox H C, Gomm J J, Coombes R C
Abstract excerpt
We have raised specific antibodies to the second immunoglobulin-like domain of fibroblast growth factor receptors (FGFRs) and used these to investigate the expression and subcellular localization of FGFR-1, -2, -3, and -4 in breast epithelial cells. All four receptors classes could be detected in...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Breast
- Breast Neoplasms
- Cell Line
- Cell Nucleus
- Chlorocebus aethiops
- Codon
- DNA Primers
- Epithelium
- Exons
- Female
- Fibroblast Growth Factors
- Fluorescent Antibody Technique
- Genetic Variation
- Humans