Article
Carbonyl (phenone) reductase in human liver: inter-individual variability.
Pharmacogenetics - 1 Apr 1993
Wong J M, Kalow W, Kadar D, Takamatsu Y, Inaba T
Abstract excerpt
The enzyme family carbonyl reductase, which catalyses the reduction of xenobiotic as well as endogenous ketones and aldehydes, has not been very well studied in terms of its biological functions and structural aspects. The aim of the present study was to check for the occurrence of inter-individual variability of carbonyl reductase activity in human liver. In vitro metabolism of p-nitroacetophenone (PNAP, a...
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