Mitochondrial diseases: genotype versus phenotype.

doi:10.1016/0168-9525(93)90207-x

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Article

Mitochondrial diseases: genotype versus phenotype.

Trends in genetics : TIG - 1 Apr 1993

Wallace D C

Abstract excerpt

Recently, a variety of degenerative diseases have been attributed to mutations in mitochondrial DNA. Even though these mutations are inherited and present throughout the body, they frequently cause late-onset, tissue-specific disease. This may be explained by a combination of the tissue-specific...

Topics

DNA, Mitochondrial
Extrachromosomal Inheritance
Genetic Diseases, Inborn
Genotype
Humans
Mutation
Oxidative Phosphorylation
Phenotype

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