Article
[A comparison of the efficacy of the anticlastogenic action of interferon and of the radiation-adaptive response].
Radiobiologiia - 1 Jan 2000
Makedonov G P, Alekhina N I, Tskhovrebova L V, Zasukhina G D
Abstract excerpt
Human lymphocytes, in the in vitro culture, exposed to X-rays (0.05 Gy) or treated with lymphoblastoid interferon (50 IE/ml) in phase G1 were less susceptible to induction of chromosome aberrations, of a chromosome type, by subsequent gamma-radiation (2 Gy) than those exposed to 2 Gy radiation only. The anticlastogenic effect of the pretreatment with interferon was considerably higher than that of preirradiation...
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