Article
Modification of DNA repair by human interferons.
Acta biologica Hungarica - 1 Jan 1990
Makedonov G P, Chekova V V, Yakubovskaya E L, Zasukhina G D
Abstract excerpt
We have found a new biological function of interferons, namely, their capacity to protect human cells from the action of some physical and chemical mutagens. To evaluate the protective effect of interferons the following criteria were applied: formation of sister chromatid exchanges (SCE) and chromosomal aberrations (CA), as well as viability of cells and intensity of DNA repair synthesis. Pretreatment of cells...
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