Article
[The cytogenetic effect of natural modifiers of mutagenesis in a human lymphocyte culture: the modification of the mutagenic effect by recombinant interferon in vitro in the lymphocytes of bronchial asthma patients and of healthy donors].
TSitologiia i genetika - 1 Jan 2000
Movsesian E S, Sarkisian T F, Arutiunian R M
Abstract excerpt
The significant protective effect of recombinant interferon in the cultures of lymphocytes of healthy donors and patients with bronchial asthma has been revealed. The cytogenetic damage were stimulated by alkylating agents thioTEPA and photrin during their administration at the stages Gi-S of the...
Topics
- Asthma
- Aziridines
- Cells, Cultured
- Chromosome Aberrations
- Dose-Response Relationship, Drug
- Drug Interactions
- Humans
- Interferons
- Lymphocytes
- Metaphase
- Mutagens
- Mutation
- Recombinant Proteins
- Thiotepa