Article
Amino-acylation site mutations in amino acid-activating domains of surfactin synthetase: effects on surfactin production and competence development in Bacillus subtilis.
Journal of bacteriology - 1 Jun 1993
D'Souza C, Nakano M M, Corbell N, Zuber P
Abstract excerpt
The part of the srfA operon of Bacillus subtilis that contains the region required for competence development is composed of the first four amino acid-activating domains which are responsible for the incorporation of Glu, Leu, D-Leu, and Val into the peptide moiety of the lipopeptide surfactin. S...
Topics
- Amino Acids
- Antibiotics, Antineoplastic
- Bacillus subtilis
- Bacterial Proteins
- Base Sequence
- DNA Mutational Analysis
- Lipopeptides
- Molecular Sequence Data
- Mutation
- Operon
- Peptide Synthases
- Peptides, Cyclic
- Recombinant Fusion Proteins
- Signal Transduction
- Transformation, Genetic