Article
Immunophenotypic and genotypic characterization of B-cell chronic lymphocytic leukemia patients from northern Italy.
Haematologica - 1 Jan 2000
Gandini D, Lanza F, Latorraca A, Levato F, Del Senno L, Castoldi G
Abstract excerpt
BACKGROUND AND METHODS: Immunoglobulin (Ig) gene expression and rearrangements provide information about cell lineage, clonality and differentiation of neoplastic lymphoid cells. We performed flow cytometry and Southern blot analysis in 25 patients with chronic lymphocytic leukemia (CLL) from the Po River delta region (Northern Italy), in order to correlate surface immunological phenotype and heavy and light...
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