Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low codon bias and high rates of synonymous substitution in Drosophila hydei and D. melanogaster histone genes.

Molecular biology and evolution - 1 Mar 1993

Fitch D H, Strausbaugh L D

Abstract excerpt

We have evaluated codon usage bias in Drosophila histone genes and have obtained the nucleotide sequence of a 5,161-bp D. hydei histone gene repeat unit. This repeat contains genes for all five histone proteins (H1, H2a, H2b, H3, and H4) and differs from the previously reported one by a second EcoRI site. These D. hydei repeats have been aligned to each other and to the 5.0-kb (i.e., long) and 4.8-kb (i.e.,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Codon
Share to Drosophila

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Molecular Sequence Data

Share to Mutation

Share to Species Specificity

Source

Identifiers

PMID: 8487638
DOI: 10.1093/oxfordjournals.molbev.a040011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low codon bias and high rates of synonymous substitution in Drosophila hydei and D. melanogaster histone genes.PMID 8487638Read ↗

Strong purifying selection at synonymous sites in D. melanogaster.Semantic proximity Read ↗

Purifying selection and birth-and-death evolution in the histone H4 gene family.Semantic proximity Read ↗

Distinct responses to rare codons in select <i>Drosophila</i> tissuesSemantic proximity Read ↗

Intragenic Hill-Robertson interference influences selection intensity on synonymous mutations in Drosophila.Semantic proximity Read ↗

Factors affecting synonymous codon usage of housekeeping genes in Drosophila melanogaster.Semantic proximity Read ↗

Codon usage in twelve species of Drosophila.Semantic proximity Read ↗

Recent and Long-Term Selection Across Synonymous Sites in Drosophila ananassae.Semantic proximity Read ↗

Patterns of mutation and selection at synonymous sites in Drosophila.Semantic proximity Read ↗

Histone H1 genes and histone gene clusters in the genus Drosophila.Semantic proximity Read ↗

Switch in codon bias and increased rates of amino acid substitution in the Drosophila saltans species group.Semantic proximity Read ↗

Difference in larval type explains patterns of nonsynonymous substitutions in two ancient paralogs of the histone H3 gene in sea stars.Semantic proximity Read ↗

Determinants of substitution rates in mammalian genes: expression pattern affects selection intensity but not mutation rate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.