Article
The glutathione S-transferases: polymerase chain reaction studies on the frequency of the GSTM1 0 genotype in patients with pituitary adenomas.
Carcinogenesis - 1 Apr 1993
Fryer A A, Zhao L, Alldersea J, Boggild M D, Perrett C W, Clayton R N, Jones P W, Strange R C
Abstract excerpt
The frequency of the GSTM1 0 polymorphism at the glutathione S-transferase M1 locus has been determined in controls and patients with pituitary adenomas by using the polymerase chain reaction to amplify genomic DNA in the exon 4-5 region of the gene. The frequency of the genotype in patients with prolactinomas, non-functional adenomas, corticotrophinomas and somatotrophinomas varied between 52-67% compared with...
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