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Article

Structural organization of the human isovaleryl-CoA dehydrogenase gene.

Genomics - 1 Mar 1993

Parimoo B, Tanaka K

Abstract excerpt

Isovaleryl-CoA dehydrogenase (IVD) catalyzes the third step in leucine catabolism. The genetic deficiency of IVD causes isovaleric acidemia. The functional IVD gene spans approximately 15 kb and consists of 12 exons and 11 introns, with the exon size ranging from 52 to 728 bp. The poly(A) addition site begins 21 nucleotides downstream of this signal. The 5'-flanking region contained typical promoter elements such...

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Source

Identifiers

PMID: 8468053
DOI: 10.1006/geno.1993.1111

Genes

IVD
CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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