Article
Chemotherapeutic failure: resistance or insensitivity?
Annals of internal medicine - 15 Apr 1993
Braverman A S
Abstract excerpt
Immunocyte and germ cell neoplasms, often curable by chemotherapy, arise from normal tissues most vulnerable to the effects of cytotoxic drugs; generalizing from these results to treating other tumors with such agents may not be entirely valid. Our limited success in treating epithelial neoplasms may be due to insensitivity rather than to drug resistance. Well-designed attempts to overcome resistance have been...
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