Article
Identification of the Cl(-)-binding site in the human red and green color vision pigments.
Biochemistry - 9 Mar 1993
Wang Z, Asenjo A B, Oprian D D
Abstract excerpt
Chloride ions are known to bind and alter the absorption spectra of some but not all visual pigments. In this report, the human red and green color vision pigments are shown to bind Cl- and to undergo a large red shift in their absorption maxima. Mutation of 18 different positively charged amino...
Topics
- Amino Acid Sequence
- Animals
- Binding Sites
- Cell Line
- Chlorides
- Eye Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Protein Conformation
- Retinal Pigments
- Rod Opsins
- Sequence Homology, Amino Acid