Article
Role of perlecan in skeletal development and diseases.
Glycoconjugate journal - 1 Jan 2000
Hassell John, Yamada Yoshihiko, Arikawa-Hirasawa Eri
Abstract excerpt
Perlecan, a large heparan sulfate proteoglycan (HSPG), is present in the basement membrane and other extracellular matrices. Its protein core is 400 kDa in size and consists of five distinct structural domains. A number of in vitro studies suggest multiple functions of perlecan in cell growth and...
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