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Article

Colchicine Disrupts the Cytoskeleton of Rat Testis Seminiferous Epithelium in a Stage-Dependent Manner1

1 Jan 1993

Abstract excerpt

Sertoli cell microtubules play an important role in the process of spermatogenesis. We investigated the effects of colchicine, a microtubule-disrupting agent, on the seminiferous epithelium. Rats were injected intratesticularly with 0.004-40 micrograms colchicine/testis. Colchicine had a dose-related effect on seminiferous tubule fluid secretion and completely blocked secretion at a dose of 40 micrograms...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Identifiers

PMID: 8418902
DOI: 10.1095/biolreprod48.1.143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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