Article
A Saccharomyces cerevisiae RAD52 allele expressing a C-terminal truncation protein: activities and intragenic complementation of missense mutations.
Genetics - 1 Jan 1993
Boundy-Mills K L, Livingston D M
Abstract excerpt
A nonsense allele of the yeast RAD52 gene, rad52-327, which expresses the N-terminal 65% of the protein was compared to two missense alleles, rad52-1 and rad52-2, and to a deletion allele. While the rad52-1 and the deletion mutants have severe defects in DNA repair, recombination and sporulation,...
Topics
- Alleles
- Crossing Over, Genetic
- DNA Repair
- Diploidy
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Homozygote
- Mitosis
- Mutation
- Plasmids
- Recombination, Genetic