Excess histidine enzymes cause AICAR-independent filamentation in Escherichia coli.

doi:10.1007/BF00280385

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Article

Excess histidine enzymes cause AICAR-independent filamentation in Escherichia coli.

Molecular & general genetics : MGG - 1 Sept 1993

Frandsen N, D'Ari R

Abstract excerpt

High-level expression of the hisHAFI genes in Escherichia coli, cloned under the control of an IPTG-inducible promoter, caused filamentation, as previously reported in Salmonella typhimurium. We speculated that this filamentation might be produced by an action of the HisH and HisF enzymes on thei...

Topics

Aminoimidazole Carboxamide
Bacterial Proteins
DNA Replication
DNA, Bacterial
Enzymes
Escherichia coli
Histidine
Mutation
Plasmids
Ribonucleotides

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