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Article

Mutations affecting MHC class II binding of the superantigen streptococcal erythrogenic toxin A.

International immunology - 1 Aug 1993

Hartwig U F, Fleischer B

Abstract excerpt

Streptococcal pyrogenic exotoxin A (SPEA) is an important pathogenicity factor of group A streptococci. It is a member of the family of 'superantigens' produced by Staphylococcus aureus and Streptococcus pyogenes, and its T lymphocyte stimulating activity is involved in the pathogenesis of certai...

Topics

Amino Acid Sequence
Animals
Bacterial Proteins
Base Sequence
Exotoxins
Histocompatibility Antigens Class II
Humans
Lymphocyte Activation
Membrane Proteins
Mice
Mice, Inbred BALB C
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Streptococcus pyogenes

Structure-Activity Relationship

Superantigens

T-Lymphocytes

Source

Identifiers

PMID: 8398982
DOI: 10.1093/intimm/5.8.869

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8398982-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mutations affecting MHC class II binding of the superantigen streptococcal erythrogenic toxin A.PMID 8398982Read ↗

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